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Can Claude or ChatGPT work with Microsoft 365?

Claude now runs inside Microsoft Copilot. Here is where, who controls it, and what that means for governance.

CommercialGCCGovernance

Updated

Short answer

Yes. Anthropic's Claude models run inside Microsoft Copilot, Researcher, and Copilot Studio when an admin enables Anthropic as a Microsoft subprocessor. They are not available to federal GCC, GCC High, or DoD tenants. ChatGPT and Claude's own apps can also connect to Microsoft 365 through admin-approved connectors, under their own terms.

Claude inside Microsoft Copilot

Microsoft offers Anthropic models alongside its own in Microsoft Copilot, Researcher, Copilot Studio, Power Platform, and Copilot experiences in Word, Excel, and PowerPoint. In Copilot, indicators show when a Claude model is in use. In Copilot Studio, makers choose the model when they build an agent.

Who controls it

An AI Administrator or Global Administrator manages the setting in the Microsoft 365 admin center under Copilot settings, in "AI providers operating as Microsoft subprocessors." Admins can turn Anthropic off, or limit it to specific users and groups. Copilot Studio and Power Platform have additional controls in the Power Platform admin center.

Availability by cloud

  • Commercial: available. On by default in most regions; off by default in the EU, EFTA, and UK.
  • Non-federal GCC, such as state and local agencies: available through an admin setting added in July 2026.
  • Federal GCC, GCC High, and DoD: not available.

ChatGPT and Claude apps connected to Microsoft 365

The standalone ChatGPT and Claude apps can connect to SharePoint, OneDrive, and Outlook through connectors that an admin approves in Entra ID. That data then leaves Microsoft's boundary under the AI vendor's terms. Many organizations prefer to use Claude inside Copilot, where Microsoft 365 permissions, labels, and audit apply.

What to decide

  • Which models your organization allows, and for whom
  • Whether to approve third-party AI apps that request Microsoft 365 data
  • What your acceptable-use policy says about each

Based on Microsoft's published documentation as of October 2026. Microsoft changes names, features, and billing often; confirm details in your own tenant.

Related questions

Can Claude work inside Microsoft 365?

Yes. Anthropic's Claude models run inside Microsoft Copilot, Researcher, Copilot Studio, and Copilot in Word, Excel, and PowerPoint when an admin enables Anthropic as a Microsoft subprocessor. In most commercial regions outside the EU, EFTA, and UK, the setting is on by default.

Is Claude available in government clouds?

Only partly. Non-federal GCC customers can turn on Anthropic models through an admin setting added in July 2026. They are not available to federal customers in GCC or to anyone in GCC High or DoD.

Can ChatGPT or Claude connect directly to Microsoft 365 data?

Their own apps can connect to Microsoft 365 through connectors that an admin approves, which sends data outside Microsoft's boundary under the vendor's terms. Many organizations prefer to use Claude inside Copilot so data stays under Microsoft 365 controls.

How do admins control which AI models people use?

In the Microsoft 365 admin center under Copilot settings, admins can turn Anthropic on or off and limit it to specific users or groups. Copilot Studio adds its own model controls in the Power Platform admin center.

Train your team on this.

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  • AI Skills and Agent Instructions

    Power users, 1 day

    For the people everyone already asks for help. Write instructions once and reuse them: Copilot agents, Claude skills, and SharePoint agents built over your own content.

    $4,500from, per session

  • Microsoft 365 AI Governance and Tenant Audit

    Admins and IT, 1 day

    Find out what Copilot and your agents can reach before your staff do. Admins audit oversharing, labels, data loss prevention, agents, and Copilot settings in their own tenant.

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    Leaders, half day

    A plain-language briefing for the people who approve AI spend: what you already own, what it costs, what your staff can do with it, and what to fund next.

    $2,500from, per session

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